Warning! //
Our risk assessment system is based on the latest scientific and medical knowledge available in the most respected scientific and medical journals.
Please keep in mind that the risk calculation does not cover other than genetic factors. Environmental factors such as smoking, diet, stress, and physical activity play an important role in the development of the disease. In case your risk is low it does not guarantee that you will not have the disease, or in case of high risk, not means you may certainly develop the disease.
Primary open-angle glaucoma
Primary open-angle glaucoma (POAG) is characterized by elevated intraocular pressure and progressive peripheral vision loss due to optic nerve damage. The disease is more prevalent and more difficult to control in African-Americans than in Europeans. In Europe glaucoma affects 1% to 2% of people aged over 50. Glaucoma is the second leading cause of blindness in the world. Typical symptoms of POAG are eye pain, blurred vision, halos around lights, and tunnel vision with gradual loss of peripheral vision in the later stages. Early diagnosis can minimize and prevent optical nerve damage. Medicated eye-drops are used to lower intraocular pressure. If the medications are ineffective or not tolerated, certain types of surgeries may be performed.
POAG risk factors: Older age / Ethnicity (Caucasian, African-American) / Myopia / Elevated intraocular pressure / Family history of glaucoma / Type 2 diabetes / Hypothyroidism / Corticosteroids use / Pseudoexfoliation / Cardiovascular disease.
Exfoliation glaucoma
Exfoliation glaucoma disease occurs in eyes with exfoliation syndrome (XFS). XFS is a disease in which the abnormal deposition of fibrillar extracellular material occurs in many ocular tissues. Patients with XFS have an increased risk of developing additional angle-closure glaucoma. Exfoliation glaucoma caused by XFS has a worse prognosis compared to primary glaucoma and requires more serious clinical treatment. Exfoliation glaucoma occurs worldwide and is strongly associated with elevated intraocular blood pressure and age. The highest prevalence is in the age group 70 and over. Recent studies have shown that glaucomas and XFS are often aspects of systemic conditions rather than isolated eye diseases. Topical medications for treatment tend to be less effective, laser therapy is frequently used. If adequate control is still not achieved, a guarded filtration may be performed.
Exfoliation glaucoma risk factors: Older age / Elevated intraocular pressure / Northern European ethnicities / Family history of glaucoma / Type 2 diabetes / Hypothyroidism / Corticosteroids use.
WELLNESS//
The secret to living healthier, longer, and more athletic is on the Genetic Passport's Wellness test panel.! What is in our Genetic Passport Wellness test panel based on molecular DNA analysis of 68 gene regions?
GENETIC PREDISPOSITIONS
1) Immune System
2) Atrial fibrillation (AF)
3) Coronary artery disease (CAD)
4) Intracranial aneurysm (IA)
5) Peripheral arterial disease (PAD)
6) Venous thromboembolism (VTE)
7) Obesity
8) Type 1 diabetes
9) Type 2 diabetes
10) Hyperthyroidism
11) Folate Metabolism
12) Gluten Intolerance
13) Lactose Intolerance
14) Sugar Consumption
15) Alzheimer
16) Osteoporosis
17) Rheumatoid arthritis
18) Primary open-angle glaucoma (POAG)
19) Exfoliating glaucoma
20) Age-related macula degeneration (AMD)
21) Vitamine B12
22) Vitamine B6
23) Vitamine D
24) Sports Performance
REPORTING
●Determining the most common 24 genetic disease risks in the world in numerical rates.
●Comparing personal risks with population risks numerically.
●Separate disclosure of the measures required to reduce the genetic and environmental risk rates for each disease.
●Explanation of the trigger factors one by one according to the risk rate for each disease.
●Descriptive information of all environmental factors necessary to minimize or even eliminate risks by risk rate for each disease.
●Nutritional and exercise recommendations for each disease.
●Emergency response warning against high-risk rates.
●Assessing the possibility of increased risk after the interaction of other genetic regions despite the low risk of disease.
●Assessing the possibility of decreasing the risk after the interaction of other genetic regions despite the high risk of disease.
GENETIC PASSPORT® CHECK-UP //
INTRODUCING THE WORLD'S MOST ADVANCED DNA TEST.
Genetic Check-Up based on molecular DNA analysis of 150 gene regions. Genetic Passport determines the risks of nearly 40 genetic diseases, ranging from cancer to Alzheimer's, sports performance to obesity, and diabetes.
GENETIC PREDISPOSITIONS
1) Breast Cancer (BC)
2) Lung Cancer (LC)
3) Colorectal Cancer (CC)
4) Gastric Cancer (GC)
5) Basal Cell Carcinoma (BCC)
6) Bladder Cancer
7) Prostate Cancer (PC)
8) Melanoma
9) Atrial fibrillation (AF)
10) Coronary artery disease (CAD)
11) Intracranial aneurysm (IA)
12) Peripheral arterial disease (PAD)
13) Venous thromboembolism (VTE)
14) Obesity
15) Type 1 diabetes
16) Type 2 diabetes
17) High blood pressure
18) Hyperthyroidism
19) Folate Metabolism
20) Gluten Intolerance
21) Lactose Intolerance
22) Sugar Consumption
23) Alzheimer
24) Osteoporosis
25) Multiple Sclerosis (MS),
26) Migraine with Aura
27) Psoriasis
28) Rheumatoid arthritis
29) The systemic lupus erythematosus (SLE)
30) Primary open-angle glaucoma (POAG)
31) Exfoliating glaucoma
32) Age-related macula degeneration (AMD)
33) Vitamine B12
34) Vitamine B6
35) Vitamine D
36) ACTN'3 (R577X)
37) ACE (I/D)
ANALYZED GENE REGIONS
Alzheimer disease APOE
Alzheimer disease APOE
Atrial fibrillation 4q25
Atrial fibrillation PITX2
Basal cell carcinoma PADI6 rs7538XXX
Basal cell carcinoma Intergenic rs801XXX
Bladder cancer TACC3
Bladder cancer MYC
Breast cancer TP53
Breast cancer RAD51B
Breast cancer ATM rs1800XXX
Breast cancer ATM rs1800XXX
Breast cancer ATM rs1800XXX
Breast cancer ATM rs1801XXX
Breast cancer ATM rs3092XXX
Breast cancer ATM rs3218XXX
Breast cancer ATM rs3218XXX
Breast cancer TNRC9
Breast cancer BRCA1
Breast cancer ATM
Breast cancer BRCA1 rs80357XXX
Breast cancer BRCA2
Celiac disease HLA-DQA1
Celiac disease HLA-DRA
Celiac disease Intergenic rs4639XXX
Celiac disease Intergenic rs4713XXX
Celiac disease Intergenic rs7454XXX
Celiac disease HLA-DQB1
Colorectal cancer SMAD7
Colorectal cancer Intergenic rs4779XXX
Colorectal cancer SMAD7
Colorectal cancer Intergenic rs6983XXX
Colorectal cancer TCF7L2
Coronary artery disease LPA
Coronary artery disease CDKN2B-AS1
Coronary artery disease Intergenic rs10757XXX
Coronary artery disease CDKN2B-AS1 rs2383XXX
Coronary artery disease CDKN2B-AS1 rs2383XXX
Coronary artery disease LPA
Exfoliating glaucoma LOXL1
Exfoliating glaucoma LOXL1 rs3825XXX
Folate Metabolism MTHFR
Gallstone disease ABCG8 rs11887XXX
Gastric cancer MTHFR rs1801XXX
Graves' disease IL-23R rs10889XXX
Graves' disease TNF-α rs1800XXX
Graves' disease TNF-α rs1800XXX
Graves' disease IL-23R rs2201XXX
Graves' disease IL-23R rs7530XXX
Intracranial aneurysm SOX17 rs10958XXX
Intracranial aneurysm CDKN2A/CDKN2B
Lactose intolerance MCM6 rs4988XXX
Lung cancer CHRNA3 rs1051XXX
Lung cancer HYKK rs8034XXX
Lung cancer CHRNA5 rs951XXX
Male pattern baldness Intergenic
Male pattern baldness Intergenic rs6625XXX
Melanoma MC1R rs1805XXX
Migraine with aura MTHFR rs1801XXX
Multiple sclerosis ILR2A
Multiple sclerosis HLA-DRA
Multiple sclerosis IL7R rs6897XXX
Obesity MC4R
Obesity MC4R
Obesity APOA2
Obesity PCSK1
Obesity APOA5
Obesity SH2B1
Osteoporosis LRP5 rs3736228
Osteoporosis LRP5 rs4988321
Peripheral arterial disease CHRNA5
Primary open-angle glaucoma SIX1
Primary open-angle glaucoma ATOH7
Primary open-angle glaucoma CAV1-CAV2
Primary open-angle glaucoma TMCO1
Prostate cancer FUNDC2P2
Prostate cancer Intergenic rs16901XXX
Prostate cancer CASC17
Prostate cancer Intergenic
Psoriasis TNF-α
Psoriasis LCE3D
Rheumatoid arthritis TRAF1
Rheumatoid arthritis Intergenic rs6457617
Rheumatoid arthritis STAT4
Sugar consumption SLC2A2
Systemic lupus erythematosus STAT4
Systemic lupus erythematosus IRF5
Systemic lupus erythematosus ITGAM
Systemic lupus erythematosus TNF-a
Systemic lupus erythematosus HLA-DQA1
Systemic lupus erythematosus SKIV2L
Systemic lupus erythematosus STAT4
Systemic lupus erythematosus ITGAM
Type 1 diabetes PTPN22
Type 1 diabetes CLEC16A
Type 1 diabetes STAT4
Type 1 diabetes HLA-DQA1
Type 2 diabetes CDKN2B
Type 2 diabetes Intergenic
Type 2 diabetes TCF7L2
Type 2 diabetes SLC30A8
Type 2 diabetes PPARG
Type 2 diabetes TCF7L2
Type 2 diabetes Intergenic
Type 2 diabetes Intergenic
Type 2 diabetes FTO rs9939XXX
Venous thromboembolism F2 rs1799XXX
Venous thromboembolism F5
Vitamin B12 FUT2
Vitamin B6 ALPL
Vitamin D CYP2R1
Vitamin D CYP2R1
Vitamin D GC
Vitamin D GC
Muscle type ACTN3
Cardiyac capacity ACE
REPORTING
●Determining the most common 24 genetic disease risks in the world in numerical rates.
●Comparing personal risks with population risks numerically.
●Separate disclosure of the measures required to reduce the genetic and environmental risk rates for each disease.
●Explanation of the trigger factors one by one according to the risk rate for each disease.
●Descriptive information of all environmental factors necessary to minimize or even eliminate risks by risk rate for each disease.
●Nutritional and exercise recommendations for each disease.
●Emergency response warning against high-risk rates.
●Assessing the possibility of increased risk after the interaction of other genetic regions despite the low risk of disease.
●Assessing the possibility of decreasing the risk after the interaction of other genetic regions despite the high risk of disease.